I have been having a Intel P4 2.0Ghz unit be doing the folding@home Program. Right now I don't want to fold on my Main Rig because Nvidia messed up something in my Driver for my Card and now I get every few minutes my Video and Sound locks up for a few seconds and continue. I found out it was the Video Driver because when I uninstalled the Driver and used Microsofts FailSafe Driver no issues.
Also on a Autism Forum I go on I ran into this Puzzle Game http://fold.it/
it does deal with Folding@home.