Going to need more details on this.
What distribution specifically, what exactly do you want it to run, 32 bit or 64 bit, etc?
What's popular? What's the easiest way for a total Linux noob to install the alternate OS and use Wine to access common Windows programs? How do they do that?
I would assume 32-bit, given its popularity amongst most normal users.
As far as installing wine goes, 32 or 64 bit only matters so far as package choice. This would be a good little blurb for a sidebar.
Edit: Please ignore the next two paragraphs. Once again, I have posted without reading the entire thread. Mea culpa.
Do you want the article to include installing linux AND wine? That would make a very long or very shallow article .. and Will has covered the installation of a linux OS relatively recently.
The alternative would be to focus the article on the installation of wine and set-up of several popular games (ideally very different games so that the reader has an indication of what is necessary).
Will the article focus on wine (free) or Cedega (not free, but much more robust)? What about benchmarking? The same PC running a game under XP and wine / linux would provide interesting (though statistically weak) data.
Maybe I should just shut-up and polish my article on installing wireless cards using the ndiswrapper.
Do we have a time-frame? I'm busy, but this is exciting enough that I can pull a sleepless night or two if it needs to be done this week. (Edit: Again, please ignore)